Picosecond Laser Ablation of Polyhydroxyalkanoates (PHAs): Comparative Study of Neat and Blended Material Response

Polyhydroxyalkanoates (PHAs) have emerged as a promising biodegradable and biocompatible material for scaffold manufacturing in the tissue engineering field and food packaging. Surface modification is usually required to improve cell biocompatibility and/or reduce bacteria proliferation. Picosecond laser ablation was applied for surface micro structuring of short- and medium-chain length-PHAs and its blend. The response of each material as a function of laser energy and wavelength was analyzed. Picosecond pulsed laser modified the surface topography without affecting the material properties. UV wavelength irradiation showed halved ablation thresholds compared to visible (VIS) wavelength, revealing a greater photochemical nature of the ablation process at ultraviolet (UV) wavelength. Nevertheless, the ablation rate and, therefore, ablation efficiency did not show a clear dependence on beam wavelength. The different mechanical behavior of the considered PHAs did not lead to different ablation thresholds on each polymer at a constant wavelength, suggesting the interplay of the material mechanical parameters to equalize ablation thresholds. Blended-PHA showed a significant reduction in the ablation threshold under VIS irradiation respect to the neat PHAs. Picosecond ablation was proved to be a convenient technique for micro structuring of PHAs to generate surface microfeatures appropriate to influence cell behavior and improve the biocompatibility of scaffolds in tissue engineerin

Scaling relations of the colour-detected cluster RzCS 052 at z=1.016 and of some other high redshift clusters

We report on the discovery of the z=1.016 cluster RzCS 052 using a modified red sequence method, followup spectroscopy and X-ray imaging. This cluster has a velocity dispersion of 710+-150 km/s, a virial mass of 4.0e14 Msol (based on 21 spectroscopically confirmed members) and an X-ray luminosity of (0.68+- 0.47)e44 ergs/s in the [1-4] keV band. This optically selected cluster appears to be of richness class 3 and to follow the known L_X-sigma_v relation for high redshift X-ray selected clusters. Using these data, we find that the halo occupation number for this cluster is only marginally consistent with what expected assuming a self-similar evolution of cluster scaling relations, suggesting perhaps a break of them at z~1. We also rule out a strong galaxy merging activity between z=1 and today. Finally, we present a Bayesian approach to measuring cluster velocity dispersions and X-ray luminosities in the presence of a background: we critically reanalyze recent claims for X-ray underluminous clusters using these techniques and find that the clusters can be accommodated within the existing L_X -sigma_v relation.Comment: MNRAS, in pres

Prevalence of thoracic vertebral malformations in french bulldogs, pugs and english bulldogs with and without associated neurological deficits

Congenital vertebral malformations are common incidental findings in small breed dogs. This retrospective observational study evaluated the type and prevalence of thoracic vertebral malformations in 171 neurologically normal and 10 neurologically abnormal screw-tailed brachycephalic dogs. Neurologically normal dogs underwent CT for reasons unrelated to spinal disease, while affected dogs underwent MRI. Imaging studies were reviewed and vertebral malformations including hemivertebrae, block vertebrae, transitional vertebrae, and spina bifida were documented. The group of clinically normal dogs consisted of 62 French bulldogs, 68 Pugs and 41 English bulldogs. The group of affected dogs consisted of one French bulldog and nine Pugs. Overall, 80.7% of neurologically normal animals were affected by at least one vertebral malformation. There was a significant influence of breed, with thoracic vertebral malformations occurring more often in neurologically normal French bulldogs (P < 0.0001) and English bulldogs (P = 0.002). Compared to other breeds, hemivertebrae occurred more often in neurologically normal French bulldogs (93.5%; P < 0.0001 vs. Pugs; P = 0.004 vs. English bulldogs) and less often in neurologically normal Pugs (17.6%; P = 0.004 vs. English bulldogs). Neurologically normal Pugs were more often diagnosed with transitional vertebrae and spina bifida compared to other breeds (P < 0.0001 for both malformations). Of Pugs included in the study, 4.7% were diagnosed with clinically relevant thoracic vertebral malformations. When compared to the general veterinary hospital population, this was significantly more than the other two breeds (P = 0.006). This study indicates that thoracic vertebral malformations occur commonly in neurologically normal screw-tailed brachycephalic dogs. While hemivertebrae are often interpreted as incidental diagnostic findings, they appear to be of greater clinical importance in Pugs compared to other screw-tailed brachycephalic breeds

Light to Mass Variations with Environment

Large and well defined variations exist between the distribution of mass and the light of stars on extragalactic scales. Mass concentrations in the range 10^12 - 10^13 M_sun manifest the most light per unit mass. Group halos in this range are typically the hosts of spiral and irregular galaxies with ongoing star formation. On average M/L_B ~ 90 M_sun/L_sun in these groups . More massive halos have less light per unit mass. Within a given mass range, halos that are dynamically old as measured by crossing times and galaxy morphologies have distinctly less light per unit mass. At the other end of the mass spectrum, below 10^12 M_sun, there is a cutoff in the manifestation of light. Group halos in the range 10^11 - 10^12 M_sun can host dwarf galaxies but with such low luminosities that M/L_B values can range from several hundred to several thousand. It is suspected that there must be completely dark halos at lower masses. Given the form of the halo mass function, it is the low relative luminosities of the high mass halos that has the greatest cosmological implications. Of order half the clustered mass may reside in halos with greater than 10^14 M_sun. By contrast, only 5-10% of clustered mass would lie in entities with less than 10^12 M_sun.Comment: 15 pages, 9 figures, 2 tables, Accepted Astrophysical Journal 619, 000, 2005 (Jan 1

Climate Modeling of a Potential ExoVenus

The planetary mass and radius sensitivity of exoplanet discovery capabilities has reached into the terrestrial regime. The focus of such investigations is to search within the Habitable Zone where a modern Earth-like atmosphere may be a viable comparison. However, the detection bias of the transit and radial velocity methods lies close to the host star where the received flux at the planet may push the atmosphere into a runaway greenhouse state. One such exoplanet discovery, Kepler-1649b, receives a similar flux from its star as modern Venus does from the Sun, and so was categorized as a possible exoVenus. Here we discuss the planetary parameters of Kepler-1649b with relation to Venus to establish its potential as a Venus analog. We utilize the general circulation model ROCKE-3D to simulate the evolution of the surface temperature of Kepler-1649b under various assumptions, including relative atmospheric abundances. We show that in all our simulations the atmospheric model rapidly diverges from temperate surface conditions towards a runaway greenhouse with rapidly escalating surface temperatures. We calculate transmission spectra for the evolved atmosphere and discuss these spectra within the context of the James Webb Space Telescope (JWST) Near-Infrared Spectrograph (NIRSpec) capabilities. We thus demonstrate the detectability of the key atmospheric signatures of possible runaway greenhouse transition states and outline the future prospects of characterizing potential Venus analogs.Comment: 11 pages, 4 figures, 1 table, accepted for publication in the Astrophysical Journal. The data from this paper are open source and are available from the following data portals: https://portal.nccs.nasa.gov/GISS_modelE/ROCKE-3D/Climate_Modeling_of_a_Potential_ExoVenus https://archive.org/details/Climate_Modeling_of_a_Potential_ExoVenu

WQ 2059-247: An unusual high redshift X-ray cluster

X-ray, optical, and radio observations of a high redshift, Bautz-Morgan type I cluster of galaxies are reported. The cD galaxy contains a powerful, flat spectrum radio source coincident with the possibly stellar nucleus. The cluster is an extremely luminous X-ray source; however, unlike nearby luminous X-ray clusters the X-ray spectrum appears to be rather soft. Two possible interpretations of the soruces are suggested: either the intracluster gas is much cooler in high redshift clusters because they are less relaxed, or the X-ray and radio emissions from WQ 2059-247 are the result of a non thermal QSO/BL Lac type object in the nucleus of the cD

Climate Modeling of a Potential Exovenus

The planetary mass and radius sensitivity of exoplanet discovery capabilities has reached into the terrestrial regime. The focus of such investigations is to search within the Habitable Zone where a modern Earth-like atmosphere may be a viable comparison. However, the detection bias of the transit and radial velocity methods lies close to the host star where the received flux at the planet may push the atmosphere into a runaway greenhouse state. One such exoplanet discovery, Kepler-1649b, receives a similar flux from its star as modern Venus does from the Sun, and so was categorized as a possible exoVenus. Here we discuss the planetary parameters of Kepler-1649b in relation to Venus to establish its potential as a Venus analog. We utilize the general circulation model ROCKE-3D to simulate the evolution of the surface temperature of Kepler-1649b under various assumptions, including relative atmospheric abundances. We show that in all our simulations the atmospheric model rapidly diverges from temperate surface conditions toward a runaway greenhouse with rapidly escalating surface temperatures. We calculate transmission spectra for the evolved atmosphere and discuss these spectra within the context of the James Webb Space Telescope Near-Infrared Spectrograph capabilities. We thus demonstrate the detectability of the key atmospheric signatures of possible runaway greenhouse transition states and outline the future prospects of characterizing potential Venus analogs